For more than 170 years, the Sisters of the Most Precious Blood of O’Fallon have strived to continue the mission of Jesus and to experience Christ’s redeeming presence as we affirm and empower one another and those we serve. We seek to bring the reconciling presence of Jesus to the world.

Men and women are often called by Jesus to form a deeper commitment with God, with the Sisters of the Most Precious Blood, and with these ministries. Read more about joining us as a CPPS Partner in Mission.


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Contact Us

(636) 240-6010

204 North Main Street
O’Fallon, MO 63366-2299


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